Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 17231-51-5, name is 3-Amino-6-bromopyrazine-2-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 3-Amino-6-bromopyrazine-2-carbonitrile
Step 2: synthesis of 3,6-dibromopyrazine-2-carbonitrile (15) To a solution of copper(ii) bromide (1.432 g, 6.41 mmol) and tert-butylnitrite (0.769 mL, 6.41 mmol) in acetonitrile (40 mL) was added 3-amino-6-bromopyrazine-2-carbonitrile 14 (1.16 g, 5.83 mmol) in portions (in 2 h). The reaction was stirred for 2 h at 50 C. Quenched with 2N HCl solution and the resulting precipitate was collected. Purification by chromatography (CH2Cl2) gave pure 3,6-dibromopyrazine-2-carbonitrile 15 (820 mg, 53.5%). 1H-NMR (400 MHz, CDCl3) 8.66 (s, 1H). (m/z)=261, 263 and 265 (M+H)+.
According to the analysis of related databases, 17231-51-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Folmer, Brigitte Johanna Bernita; Man, de Adrianus Petrus Antonius; Gernette, Elisabeth Sophia; Corte Real Goncalves Azevedo, Rita; Ibrahim, Hemen; US2013/79341; (2013); A1;,
Pyrazine – Wikipedia,
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