Synthetic Route of 123-32-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 123-32-0, name is 2,5-Dimethylpyrazine belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.
Preparation of 3,6-dimethyl-2- (4-isopropyl) benzoyl pyrazine, comprising the steps of: (1) 2,5-dimethyl pyrazine take 0.2mmol, 4- benzoyl-carboxylic acid isopropyl 0.4mmol, 0.02 mmol silver phosphate, potassium persulfate 5mL reaction tube was placed 0.4mmol, 1.4mL was added di methylene chloride, 0.6 mL of distilled water was added, and the mixture was placed in an oil bath at 40 heated, reaction 24h, cooled to room temperature to obtain a reaction solution;(2) The step (1) the resulting reaction mixture was directly concentrated to give a concentrate, the concentrate with ethyl acetate / petroleum ether = 1/2 (v / v) as the developing solvent, separation by thin layer chromatography to give 20 mg desired product in 40% yield.
The synthetic route of 2,5-Dimethylpyrazine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Henan Agricultural University; Wu Zhiyong; Zhao Mingqin; Li Yuan; (10 pag.)CN108101856; (2018); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem