Adding a certain compound to certain chemical reactions, such as: 297172-19-1, name is 5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazine, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 297172-19-1, Computed Properties of C6H9N3
EXAMPLE 3 5-[5,6-Dihydroimidazo[1,5-a]pyrazin-7(8H)-yl]-3-(2-fluorophenyl)-[1,2,3]triazolo[1,5-a]quinazoline Prepared from 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine as described for Example 1, step c (0.033 g, 37%). deltaH (360 MHz; CDCl3) 4.07 (2H, dd, J=6 and 6), 4.44 (2H, dd, J=6 and 6), 4.92 (2H, s), 6.93 (1H, s), 7.22-7.32 (2H, m), 7.37-7.41 (1H, m), 7.60 (1H, s), 7.69 (1H, dd, J=8 and 8), 7.96 (1H, dd, J=8 and 8), 8.05-8.09 (2H, m), 8.73 (1H, d, J=8); m/z (ES+) 386 (M+H+).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazine, and friends who are interested can also refer to it.
Reference:
Patent; Chambers, Mark Stuart; Collins, Ian James; Goodacre, Simon Charles; Hallett, David James; Jones, Philip; Keown, Linda Elizabeth; Maxey, Robert James; Street, Leslie Joseph; US2003/45532; (2003); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem