Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 23688-89-3, name is 6-Chloropyrazine-2-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C5H3ClN2O2
6-Ch[oropyrazine-2-carboxy[ic acid [CAS RN: 23688-89-3] (700 mg, 4.42 mmo[, 1 .0 eq) in 30 mL ethyl. acetate was treated with T3P solution [50 % in ethyl acetate] (6.57 mL, 11.0 mmol, 2.5 eq) and with N-hydroxyethanimidamide [CAS10 RN: 22059-22-9] (327 mg, 4.42 mmol, 1.0 eq). The resulting solution was stirredat 65 C overnight. The reaction mixture was hydrolysed and extracted with ethyl acetate (3x). The combined organic phases were washed with a saturated sodium bicarbonate solution and with brine. The phases were separated by the use of a Whatman filter. The volatile components of the resulting organic phasewere removed in vacuo and the crude material was purified via preparative HPLC under basic conditions (column: Chromatorex C18, eluent: acetonitrile / 0.2% aqueous ammonia 15:85 -> 55:45) to give 55 mg (6% yield of theory) of the title compound.UPLC-MS (Method 2): R = 0.88 mm; MS (EI0): m/z = 197 [M+H].1H-NMR (400 MHz, DMSO-d6): oe [ppm] = 9.10 (5, 1H), 9.36 (5, 1H), 1xCH3 obscured by solvent signal.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 23688-89-3.
Reference:
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; BAeRFACKER, Lars; SIEMEISTER, Gerhard; HEINRICH, Tobias; PRECHTL, Stefan; STOeCKIGT, Detlef; ROTTMANN, Antje; WO2015/113927; (2015); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem