Application of 233278-56-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 233278-56-3, name is 5,6,7,8-Tetrahydro[1,2,4]triazolo[1,5-a]pyrazine belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.
EXAMPLE 4 5-[5,6-Dihydro[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl]-3-(2-fluorophenyl)-[1,2,3]triazolo[1,5-a]quinazoline Prepared from 5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyrazine as described for Example 1, step c (0.047 g, 53%). Found: C, 62.52; H, 3.96; N, 29.10. C20H15FN8 requires C, 62.17; H, 3.91; N, 29.00%. deltaH (360 MHz; CDCl3) 4.16 (2H, dd, J=5 and 5), 4.61 (2H, dd, J=5 and 5), 5.02 (2H, s), 7.22-7.33 (2H, m), 7.40-7.42 (1H, m), 7.71 (1H, dd, J=8 and 8), 7.95-8.08 (4H, m), 8.75 (1H, d, J=8); m/z (ES+) 387 (M+H+).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5,6,7,8-Tetrahydro[1,2,4]triazolo[1,5-a]pyrazine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Chambers, Mark Stuart; Collins, Ian James; Goodacre, Simon Charles; Hallett, David James; Jones, Philip; Keown, Linda Elizabeth; Maxey, Robert James; Street, Leslie Joseph; US2003/45532; (2003); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem