In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4744-50-7, name is 2,3-Pyrazinecarboxylic anhydride belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below. Quality Control of 2,3-Pyrazinecarboxylic anhydride
A mixture of 1 -ethyl-7-hydroxy-2,2,4-trimethyl- 1 ,2-dihydroquinoline (1.15 mmole), l-(5- carboxypentyl)-7-hydroxy-2,2,4-trimethyl-l,2-dihydroquinoline (1.15 mmole), 2,3- pyrazinedicarboxylic anhydride (1.15 mmole) and 50 mg p-toluenesulfonic acid is stirred in propionic acid (80 mL) at 140 C for 24 hours. The solvent is removed under vacuum and the product is purified by a silica gel column eluting with MeOH/CHCl3.
The synthetic route of 4744-50-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BIOTIUM, INC.; MAO, Fei; LEUNG, Wai-Yee; CHEUNG, Ching-Ying; HOOVER, Hye Eun; WO2011/68569; (2011); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem