Adding a certain compound to certain chemical reactions, such as: 33332-28-4, name is 2-Amino-6-chloropyrazine, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 33332-28-4, HPLC of Formula: C4H4ClN3
6-Morpholinop razin-2-amineA stirred solution of 6-chloropyrazin-2-amine (0.225 g, 1.74 mmol) and morpho- line (0.227 g, 2.61 mmol) was heated at 100 C for 22 h. After cooling to 23 C, water was added to the mixture and extracted with EtOAc. The combined organics were concentrated in vacuo. The crude mixture was purified on alumina (0-50% EtOAc in hexane) to give the desired product 6-morpholinopyrazin-2- amine. Mass Spectrum (ESI) m/e = 181.1 (M + 1).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Amino-6-chloropyrazine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; AMGEN INC.; DRANSFIELD, Paul John; GONZALEZ LOPEZ DE TURISO, Felix; PATTAROPONG, Vatee; SIMARD, Jillian L.; WO2012/3264; (2012); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem