Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 71257-38-0, name is 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., name: 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine
EXAMPLE 6 2-Benzoyl-1,2,3,4-Tetrahydropyrrolo-[1,2-a]-Pyrazine To a solution of 12.2 g of 1,2,3,4-tetrahydropyrrolo-[1,2-a]-pyrazine and 22.2 g of triethylamine in 50 ml of anhydrous benzene, 15.4 g of benzoyl chloride was added in small portions at 10-15 C. The reaction mass was stirred for 3 hours at room temperature and then poured into water. The organic phase was separated, and washed with a 5% solution of sodium carbonate and then water. The solvent was removed by distillation, the residue was distilled under vacuum, and the fraction with a boiling point of 189-191 C. at 1 mm Hg was collected. The yield of the title compound was 15 g (66.5%). Nmr (CDCl3): delta3.7-3.9 (m) (4H, 3,4-CH2); 4.58 (s) (2H, 1-CH2); 5.6-5.8 (m) (1H, 7-H); 5.8-6.0 (m) (1H, 8-H); 6.2-6.4 (m) (1H, 6 -H); 7.2-7.4 (m) (5H-C6 H5). Anal. calculated for C14 H14 N2 O: C 74.31%; H 6.24%; N 12.38% and found: C 74.21%; H 6.24%; N 12.45%.
According to the analysis of related databases, 71257-38-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Russian-American Institute For New Drug Development; US5378846; (1995); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem