Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4744-50-7, name is 2,3-Pyrazinecarboxylic anhydride, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 4744-50-7
In a 250 mL three-necked flask equipped with a mechanical stirrer, a spherical condensed reflux tube was added 15 g in this order 2, 3-pyrazinedicarboxylic anhydride,13 g of 2-amino-5-chloropyridine,0.12 g of 4-dimethylaminopyridine,120 mL of xylene,At 30 C, add 202 g of triethylamine.Heated to 80 C,Reaction 8h; continue to heat up to reflux,Reaction lh.Stop heating,Mechanical stirring naturally down to room temperature,Continue to stir 2h; use ice bath cooling,Control the temperature at 0-5 C,Stir for 2 h.Filtration,The filter cake was washed once with 50 mL of 1 N diluted hydrochloric acid,50 mL of water was again washed,60 C oven drying 8h,Obtained as a white solid 22. lg,Yield 85%Purity 98%,Melting point: 232-235 C.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 4744-50-7.
Reference:
Patent; Disha Pharmaceutical Group; Weihai Disu Pharmaceutical Co., Ltd; LI, GUANGYUE; DING, YAN; (5 pag.)CN103664952; (2016); B;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem