Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2727-13-1, name is 3-Amino-6-chloropyrazine-2-carboxylic acid, A new synthetic method of this compound is introduced below., Computed Properties of C5H4ClN3O2
To a mixture of 3-amino-6-chloropyrazine-2-carboxylic acid (1 .00 g; 5.76 mmol) and triethylamine (2.40 ml; 17.3 mmol) in abs. DMF is added 2-tert-butyl-5-methyl-1 ,2-oxazol-2- ium hexafluoro-phosphate (4.93 g; 17.3 mmol). The mixture is stirred at r.t. over night. Ice- water is added. The supernatant is decanted from the resin-like product which is sufficiently pure to be further reactedESI Mass spectrum: m/z = 313 [M+H]+
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; KLEY, Joerg; HAERLE, Daniel; LINZ, Guenter; STEHLE, Sandra; WO2013/64451; (2013); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem