Electric Literature of 123-32-0, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 123-32-0 as follows.
Example 5 BSc4352: 4,4′-(1E,1’E)-2,2′-(pyrazine-2,5-diyl)bis(ethene-2,1-diyl)bis(N,N-dimethylaniline) Synthesis: 2,5-Dimethylpyrazine (0.125 g, 1.16 mmol) is dissolved in 10 ml dimethylformamide, followed by addition of 4-(dimethylamino)benzaldehyde (0.345 g, 2.32 mmol) and potassium-t-butoxide (0.26 g, 2.32 mmol). The solution is heated for 4 h to 80 C. and allowed to cool to room temperature. In this process, a solid crystallizes out. The solution containing the crystallized solid is filtered and washed with ethyl acetate. After drying under high-vacuum, 0.308 g (yield: 72%) of the product BSc4352 is obtained as red solid.1H-NMR (CDCl3, 500 MHz): delta=8.49 (s, 2H), 7.62 (d, J=16 Hz, 2H), 7.49 (d, J=8.9 Hz, 4H), 6.96 (d, J=16 Hz, 2H), 6.72 (d, J=8.9 Hz, 4H), 3.02 (s, 12H) ppm13C-NMR (CDCl3, 125 MHz): delta=149.7, 148.0, 141.7, 132.8, 127.5, 123.7, 118.7, 111.2, 39.3 ppm.
According to the analysis of related databases, 123-32-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; KLINIKUM DARMSTADT GMBH; TECHNISCHE UNIVERSITAT DARMSTADT; LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN; Schmidt, Boris; Kieser, Daniel; Bolaender, Alexander; Herms, Jochen; Haussen, Roland Heyny-Von; Gu, Jiamin; US2013/287700; (2013); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem