Adding a certain compound to certain chemical reactions, such as: 109-08-0, name is 2-Methylpyrazine, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 109-08-0, Safety of 2-Methylpyrazine
In the glove box,Mn(CO)5Br (0.005mmol), [(E)-2-(2-(1-(2-pyridyl)ethylidene)-indenyl)pyridinium](0.006mmol),Add 1.0 mL of toluene,After stirring for two hours,Add 1a (2mmol),Benzyl alcohol 2b (1mmol),After the reaction at 135 C for 48 hours, the reaction was stopped.Evaporate the solvent,Column chromatography ethyl acetate / petroleum ether (1:10),Trans-disubstituted olefin derivative 3b.The product is a white solid.The yield was 63%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Methylpyrazine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Qingdao University of Science and Technology; Zhang Chunyan; (19 pag.)CN108250153; (2018); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem