Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 6905-47-1, name is 2-Amino-6-methoxypyrazine, A new synthetic method of this compound is introduced below., Safety of 2-Amino-6-methoxypyrazine
(6-Methoxy-pyrazin-2-yl)-thiourea 6-Methoxy-pyrazin-2-ylamine (0.85 g, 6.8 mmol) is dissolved in ethanol (7 ml) and benzoylisothiocyanate (0.91 ml) is added dropwise. The mixture is heated to 80 C. with stirring for 10 minutes then allowed to cool to room temperature. The solvent is removed in vacuo and the resulting solid dissolved in 1M sodium hydroxide (15 ml) and heated under reflux for 1 hour. The resultant suspension is filtered and the solid washed with water and a little cold ethanol. The solid is dried in vacuo to yield the title compound.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Press, Neil John; Taylor, Roger John; US2004/53982; (2004); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem