Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 944709-42-6, name is 6,8-Dibromo-[1,2,4]triazolo[1,5-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C5H2Br2N4
Into a flask under an inert atmosphere of N2, were placed 6,8-dibromoimidazo[1,2-a]pyrazine (4 g, 14.44 mmol), bis(triphenylphosphine)palladium(II) dichloride (1.01 g, 1.444 mmol) and THF (120 mL). The resulting mixture was stirred at RT for 1 h before the zinc reagent solution from Step Awas added dropwise at 0 °C. The resulting mixture was stirred at RT for 16 h then quenched by the addition of sat. aq. NH4C1 (400 mL). The resulting mixture was extracted with EtOAc (3 x 200 mL). The combined organic layer was washed with brine (2 x 500 mL), dried over anhydr. Na2SO4, filtered and the filtrate was concentrated in vacuo to dryness. The residue was purified by column chromatography with EtOAc/petroleum ether (5percent-45percent) to afford thetitle compound.
According to the analysis of related databases, 944709-42-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MERCK SHARP & DOHME CORP.; WHITEHEAD, Alan; ORNOSKI, Olga; RAGHAVAN, Subharekha; BERGER, Raphaelle; GARFUNKLE, Joie; YANG, Zhiqiang; JI, Gang; JIANG, Falong; FU, Jianmin; (132 pag.)WO2017/197555; (2017); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem