Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6270-63-9, name is Pyrazin-2(1H)-one, This compound has unique chemical properties. The synthetic route is as follows., category: Pyrazines
Example 181; (1SR,2RS)-1-methyl-cyclopropane-1,2-dicarboxylic acid 2-[(5-chloro-pyridin-2-yl)-amide]1-{[2-fluoro-4-(2-oxo-pyrazin-1-yl)-phenyl]-amide}; In analogy to example 178, step 3, (1SR,2RS)-2-(5-chloro-pyridin-2-ylcarbamoyl)-1-methyl-cyclopropanecarboxylic acid methyl ester (example 178, step 2) was reacted with 1-(4-amino-3-fluoro-phenyl)-1H-pyrazin-2-one (prepared from 2-fluoro-4-iodoaniline by reaction with 1H-pyrazin-2-one, Cu(I)I, N,N’-dimethylethylenediamine and cesium carbonate in dioxane at 120 C.) to give (I SR,2RS)-1-methyl-cyclopropane-1,2-dicarboxylic acid 2-[(5-chloro-pyridin-2-yl)-amide]1-{[2-fluoro-4-(2-oxo-pyrazin-1-yl)-phenyl]-amide} as off-white solid. MS 440.3 ([M-H]-).
According to the analysis of related databases, 6270-63-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Boehringer, Markus; Zbinden, Katrin Groebke; Haap, Wolfgang; Hilpert, Hans; Himber, Jacques; Humm, Roland; Iding, Hans; Knopp, Dietmar; Panday, Narendra; Ricklin, Fabienne; Stahl, Christoph Martin; US2006/106016; (2006); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem