Adding a certain compound to certain chemical reactions, such as: 274-79-3, name is Imidazo[1,2-a]pyrazine, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 274-79-3, Recommanded Product: 274-79-3
Step 1 The indole obtained [1,2-A] pyrazine (10g, 0.08mmol) was dissolved in 100mL of ethylene glycol monomethyl ether, was added 5% palladium on carbon (2G), quickly replaced with hydrogen three times, at room temperature (20-25 ) The reaction was stirred, TLC detection reaction process, the reaction is complete after 30 hours, suction filtered through celite pad, and the filtrate was concentrated by rotary evaporation and purified by column chromatography by chromatography to give 5,6,7,8- hydrogen-imidazo [1,2-A] pyrazine 7g, the the yield of about 68%
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.
Reference:
Patent; shanghai bide pharmatech co. ltd; LI, JINFEI; HUANG, LIANGFU; LI, XINLING; WANG, MINGXIA; (5 pag.)CN103864799; (2016); B;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem