Related Products of 122-05-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 122-05-4, name is Pyrazine-2,5-dicarboxylic acid belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.
General procedure: To a mixture of tris(2-pyridylmethyl)amine, TPA (0.146g, 0.50mmol) and Cu(ClO4)2ยท6H2O (0.109g, 0.50mmol) dissolved in MeOH (20mL), 2,3-pyrazine-dicarboxylic acid (H2Pyaz2,3-dc) (0.054g, 0.25mmol) which was neutralized with LiOH (0.012g, 0.5mmol) dissolved in 5.0mL H2O was added drop by drop. The resulting solution was heated for 5min on a steam-bath, filtered through Celite and then was allowed to stand at room temperature. The resulting precipitate, which was obtained after four days was collected by filtration and recrystallized from H2O to produe aqua blue single crystals of X-ray quality. These were collected by filtration, washed with propan-2-ol, Et2O and dried in air. (overall yield: 62mg, 25% based on H2Pyaz2,3-dc)
The synthetic route of Pyrazine-2,5-dicarboxylic acid has been constantly updated, and we look forward to future research findings.
Reference:
Article; Massoud, Salah S.; Louka, Febee R.; Gazzaz, Mohammed A.; Henary, Maher M.; Fischer, Roland C.; Mautner, Franz A.; Polyhedron; vol. 111; (2016); p. 45 – 52;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem