Application of 1208082-91-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1208082-91-0, name is 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows.
Intermediate 1-05 (0.62 g, 2.13 mmol) was dissolved inCHC1 (4 mE) and N-bromosuccinimide (455 mg, 2.56mmol) was added. The reaction mixture was heated under microwave irradiation at 120 C. for 1 h. On cooling, the mixture was adsorbed in silica and purified by l3iotage column chromatography (DCMJMeOH from 100% to 95:5) to give intermediate 1-06 (720 mg, Y: 91%) as a yellow solid.
The chemical industry reduces the impact on the environment during synthesis 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine. I believe this compound will play a more active role in future production and life.
Reference:
Patent; CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO); Serrano Marugan, Manuel; Pastor Fernandez, Joaquin; Martinez Gonzalez, Sonia; Ortega Molina, Ana; Bischoff, James R.; Oyarzabal Santamarina, Julen; (220 pag.)US9993554; (2018); B2;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem