Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 33332-28-4, name is 2-Amino-6-chloropyrazine, A new synthetic method of this compound is introduced below., Quality Control of 2-Amino-6-chloropyrazine
2,2,2-Trifluoroethylisothiocyanate (6 ml.) was added to 2-amino-6-chloropyrazine (6 g.) in acetonitrile (50 ml.) and the mixture heated under reflux on the steam bath for 6 hours. On cooling the precipitated solid was recrystallized from toluene to give 2-chloro-6-(3-[2,2,2-trifluoroethyl]thioureido)pyrazine, m.p. 170°-172°.
The synthetic route of 33332-28-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Imperial Chemical Industries PLC; US4451463; (1984); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem