Research on new synthetic routes about 3,5-Dichloro-6-ethylpyrazine-2-carboxamide

The chemical industry reduces the impact on the environment during synthesis 3,5-Dichloro-6-ethylpyrazine-2-carboxamide. I believe this compound will play a more active role in future production and life.

Related Products of 313340-08-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 313340-08-8, name is 3,5-Dichloro-6-ethylpyrazine-2-carboxamide, This compound has unique chemical properties. The synthetic route is as follows.

General procedure: To a solution of compound6(0.4 mmol) and anappropriateaniline derivatives(0.2 mmol) in 1,4-dioxane, was added DIPEA (0.4 mmol). The mixture was stirred at 100oC for 12 h. The solution was diluted withwater, andfiltered. The residue was washed with water twice and dried to give the crude product as yellow solid in 42-74% yield.

The chemical industry reduces the impact on the environment during synthesis 3,5-Dichloro-6-ethylpyrazine-2-carboxamide. I believe this compound will play a more active role in future production and life.

Reference:
Article; Wang, Yueliang; Xing, Li; Ji, Yinchun; Ye, Jiqing; Dai, Yang; Gu, Wangting; Ai, Jing; Song, Zilan; Bioorganic and Medicinal Chemistry Letters; vol. 29; 6; (2019); p. 836 – 838;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem