Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 143591-61-1, name is 3-Bromo-8-chloroimidazo[1,2-a]pyrazine, A new synthetic method of this compound is introduced below., Recommanded Product: 143591-61-1
This solid was suspended in 1 : 1 dichloromethane/methanol (150 ml) and treated with solid sodium methoxide (9.8 g, 0.18 mol). The resulting mixture was then stirred at 40C for 2 h. The reaction was cooled, diluted with water (750 ml) then extracted with dichloromethane (600 ml). The organics were dried over anhydrous magnesium sulphate, filtered and concentrated to give 3-BROMO-8- METHOXYIMIDAZO [L, 2-A] PYRAZINE as a white solid (24.5 g, 89% over 2 steps):
The synthetic route of 143591-61-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MERCK SHARP & DOHME LIMITED; WO2004/41826; (2004); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem