In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1007128-70-2, name is 5,8-Dibromopyrido[3,4-b]pyrazine belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C7H3Br2N3
[0383] XII-3 (5.0 g, 17.3 mmol) and NaOMe (1.4 g, 26 mmol) were dissolved in MeOH(60 mL), and then the mixture was stirred at 60C for 0.5 h. Removed the solvent, diluted withEtOAc (100 mL), washed with brine, dried over Na2SO4 and concentrated to give XII-4 (3.7 g, 89%yield) as a light yellow solid, which was used in next step without further purification. ?H NMR(CDC13, 300 MHz) (59.05 (d, J= 1.8 Hz, 1H), 8.88 (d, J= 1.8 Hz, 1H), 8.46 (s, 1H), 4.17 (s, 3H).
The synthetic route of 1007128-70-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; INTERMUNE, INC.; RAMPHAL, Johnnie, Y.; BUCKMAN, Brad, Owen; EMAYAN, Kumaraswamy; NICHOLAS, John, Beamond; SEIWERT, Scott, D.; WO2015/153683; (2015); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem