Introduction of a new synthetic route about 850349-42-7

The chemical industry reduces the impact on the environment during synthesis Methyl imidazo[1,2-a]pyrazine-8-carboxylate. I believe this compound will play a more active role in future production and life.

Electric Literature of 850349-42-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 850349-42-7, name is Methyl imidazo[1,2-a]pyrazine-8-carboxylate, This compound has unique chemical properties. The synthetic route is as follows.

PREPARATIVE EXAMPLE 10; Commercially available Imidazo[l,2-a]pyrazine-8-carboxylic acid methyl ester (337 mg) was dissolved in 1,4-dioxane (25 ml) and H2O (58 ml) and treated with 1 M NaOH (2.4 ml). The mixture was stirred at room temperature for 45 Min and the solvents evaporated to afford the crude title compound (MH+ = 164).

The chemical industry reduces the impact on the environment during synthesis Methyl imidazo[1,2-a]pyrazine-8-carboxylate. I believe this compound will play a more active role in future production and life.

Reference:
Patent; ALANTOS PHARMACEUTICALS HOLDING, INC.; WO2008/63669; (2008); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem