1250996-70-3, name is tert-Butyl 2-(hydroxymethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate, belongs to pyrazines compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Quality Control of tert-Butyl 2-(hydroxymethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate
To a solution of 2-hydroxymethyl-5,6-dihydro-8H-imidazo[1,2-a]pyrazine-7-carboxylic acid tert-butyl ester (IV, 0.34 g, 1.34 mmol) in dry methanol (12 mL) was added 20% HQ in dioxane (18 mL) at 0 C and the resulting mixture was stirred at room temperature for 16 h. The solvent was evaporated under reduced pressure to get the crude product which was triturated with diethylether to afford the titled product as a pale-yellow solid (V, 0.25 g, 95 %). LC-MS m/z calcd for C7HuN30, 153.1 ; found 154.2 [M+H]+.
The synthetic route of 1250996-70-3 has been constantly updated, and we look forward to future research findings.