Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 84996-40-7, name is 2-Amino-3-(methylamino)pyrazine, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C5H8N4
To a mixture of 26 (3.99 g, 32.1 mmol) in THF (200 mL) was added carbonyldiimidazole (CDI; 10.4 g, 64.1 mmol), and the mixture was stirred at 70 C for 5 h. The reaction mixture was allowed to cool to room temperature and concentrated in vacuo. The residue was purified by flash column chromatography (silica gel, 0-5% MeOH in CHCl3). The residue was washed with EtOAc/n-hexane. To the residue in MeCN (100 mL) were added ethyl acrylate (7.00 mL, 64.4 mmol) and DBU (2.40 mL, 16.4 mmol), and the mixture was stirred at 50 C for 12 h under argon atmosphere. The mixture was concentrated in vacuo. The residue was purified by flash column chromatography (silica gel, 0-5% MeOH in CHCl3) to give 27 (6.11 g, 76%) as a colorless solid. 1H NMR (DMSO-d6) delta 1.10 (t, 3H, J = 7.1 Hz), 2.81 (t, 2H, J = 7.1 Hz), 3.34 (s, 3H), 4.00 (q, 2H, J = 7.1 Hz), 4.11 (t, 2H, J = 7.1 Hz), 7.95 (d, 1H, J = 3.3 Hz), 7.96 (d, 1H, J = 3.3 Hz); MS (ESI) m/z 251 [M+H]+.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 84996-40-7.