Application of 6-Chloropyrazine-2-carbonitrile

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 6-Chloropyrazine-2-carbonitrile, other downstream synthetic routes, hurry up and to see.

Adding a certain compound to certain chemical reactions, such as: 6863-74-7, name is 6-Chloropyrazine-2-carbonitrile, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6863-74-7, SDS of cas: 6863-74-7

To a suspension of 349 Raney-Ni (307 mg, 3.59 mmol,) in 25 EtOH (20 mL) was added 350 6-chloropyrazine-2-carbonitrile (1.00 g, 7.17 mmol,) and 351 tert-butoxycarbonyl tert-butyl carbonate (1.72 g, 7.88 mmol), then the reaction mixture was stirred at room temperature under H2 (45 psi) for 16 hours. The reaction mixture was filtered through celite and the filtrate was concentrated under reduced pressure to give a residue. The residue was purified by flash silica gel chromatography (eluention with 010% 56 Ethyl acetate/Petroleum ether gradient) to give 352 tert-butyl N-[(6-chloropyrazin-2-yl)methyl]carbamate (1.05 g).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 6-Chloropyrazine-2-carbonitrile, other downstream synthetic routes, hurry up and to see.