Introduction of a new synthetic route about 8-Chloro-1-iodo-3-isopropylimidazo[1,5-a]pyrazine

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1320266-92-9.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1320266-92-9, name is 8-Chloro-1-iodo-3-isopropylimidazo[1,5-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 8-Chloro-1-iodo-3-isopropylimidazo[1,5-a]pyrazine

Intermediate K (33 mg, 0.10 mmol) and NH4OH were heated to 80 C for 6 h in a microwave. The reaction mixture was concentrated in vacuo and purified using silica gel chromatography with a hexane/EtOAc gradient to yield Intermediate L (33 mg, 66% yield). ¾-NMR (300 MHz, CDC13) delta 1.4 (d, 6H, / = 5.4 Hz), 3.17-3.26 (m, 1H), 5.88 (br s, 2H), 7.02 (d, 1H, J= 5.1 Hz), 7.23 (d, 1H, J= 5.1 Hz). MS (ESI) (M+H)+ 303.2

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1320266-92-9.