Synthetic Route of 5521-55-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5521-55-1, name is 5-Methylpyrazine-2-carboxylic acid belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.
(B-96) To a solution of 5-methyl-2-pyrazine carboxylic acid (25g, 180mmol), HOBt (4.9g, 36mmol), and N,O-dimethylhydroxyamine hydrochloride (21g, 220mmol) in methylene chloride (100ml) and chloroform (400ml), were added triethylamine (30ml, 220mmol) and WSCD (41g, 220mmol) and the mixture was stirred at room temperature for 2 hours.. The solution was washed and dried, then the solvent was evaporated undr reduced pressure to give crude 5-methylpyrazine-2-carboxylic acid methoxymethylamide (30.5g). NMR(CDCl3) delta: 2.63(3H, s), 3.41(3H, s), 3.75(3H, s), 8.47(1H, s), 8.82(1H, s).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Methylpyrazine-2-carboxylic acid, other downstream synthetic routes, hurry up and to see.