Related Products of 330786-09-9, A common heterocyclic compound, 330786-09-9, name is Methyl 3,5-dichloropyrazine-2-carboxylate, molecular formula is C6H4Cl2N2O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
To a solution of compound methyl 3,5-dichloropyrazine-2-carboxylate (0.55g, 2.6mmol, l .Oeq) in dimethylformamide (5mL), cesium carbonate (0.8g, 3.1mmol, 1.2eq) and dibenzylamine (0.61g, 3.1mmol, 1.2eq) was added. Reaction mixture was stirred at room temperature for 3 hours. After completion of the reaction, reaction mixture transferred into water and extracted with ethyl acetate. Combined organic layer, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to obtain 190.1. (0.5g, 51.16%). MS(ES): m/z 368.54 [M+H]+
The synthetic route of 330786-09-9 has been constantly updated, and we look forward to future research findings.