Adding a certain compound to certain chemical reactions, such as: 16298-03-6, name is Methyl 2-aminopyrazine-3-carboxylate, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 16298-03-6, COA of Formula: C6H7N3O2
(iii) Methyl 3-amino-6-bromopyrazine-2-carboxylate: 3-Aminopyrazine-2-carboxylic acid methyl ester (200 g, 1.3 mol, 3B ScientificCorporation) was dissolved in AcOH (1 L). The solution was warmed to 50 °C and Br2 (312 g, 1.9 mol) added dropwise. When the addition was completed, the mixture was stirred at 50 °C for additional 3 hours. The reaction mixture was poured slowly to ice-water (4 L). The precipitate was filtered, washed with water and dried under a reduced pressure to afford the subtitle compound (iii) as a red brown solid (300g).1H-NMR (400 MHz, CDC13) delta 8.28 (s, 1H), 3.97 (s, 3H);HPLC Retention Time = 1.016min.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2-aminopyrazine-3-carboxylate, other downstream synthetic routes, hurry up and to see.