16298-03-6, name is Methyl 2-aminopyrazine-3-carboxylate, belongs to pyrazines compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Quality Control of Methyl 2-aminopyrazine-3-carboxylate
Acetonitrile (500 mL), Compound 1 (100 g, 0.653 mol), and NCS (87.2 g, .653 mol) were added to a 1 L three-necked flask and the mixture was heated to 82°C for 12 hours to complete the reaction. Acetonitrile was concentrated and removed, and recrystallized from petroleum ether/ethyl acetate to give a bright green crystalline Compound 2 (112.7 g, 92percent).
The synthetic route of 16298-03-6 has been constantly updated, and we look forward to future research findings.