23611-75-8, name is Methyl 6-chloropyrazine-2-carboxylate, belongs to pyrazines compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. HPLC of Formula: C6H5ClN2O2
Example 1F; (3aR,6aS)-tert-butyl 5-(6-(methoxycarbonyl)pyrazin-2-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate; The product from Example 1E (1.74 g, 10.08 mmol) was dissolved in DMSO (10 mL). The product from Example 1C (2.29 g, 10.79 mmol) and sodium carbonate (1.61 g, 15.19 mmol) were added to the reaction mixture. The reaction was stirred at 120 C. for 16 h. The reaction was then allowed to cool to ambient temperature, diluted with water (100 mL) and extracted with CH2Cl2 (4×100 mL). The organic extracts were combined and washed with water (100 mL) and brine (100 mL), dried over MgSO4, filtered and concentrated under vacuum. The residue was purified by silica gel chromatography (EtOAc, Rf=0.36) to afford the title compound as a thick oil that slowly solidified (2.78 g, 78%). MS (DCI/NH3) m/z 349 (M+H)+.
The synthetic route of 23611-75-8 has been constantly updated, and we look forward to future research findings.