Reference of 886860-50-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 886860-50-0, name is 2-Amino-5-iodopyrazine, This compound has unique chemical properties. The synthetic route is as follows.
5-iodopyrazine-2-amine (18.4 g, 83.3 mmol), copper iodide (3.2 g, 16.7 mmol), 1.10-phenanthroline (6.6 g, 33.3 dissolved mmol) and sodium ethoxide (8.5 g,125 mmol) in ethanol (160 mL), 5 hours heated and stirred at 80 . After filtering off the unwanted materials, and concentrated under reducedpressure. The obtained residue was purified by silica gel column chromatography (hexane: ethyl acetate = 2: 1) as eluant to afford the title compound(2.51 g, 22%) as a white solid.
The chemical industry reduces the impact on the environment during synthesis 2-Amino-5-iodopyrazine. I believe this compound will play a more active role in future production and life.