Some scientific research about 5-Bromo-3-methoxypyrazin-2-amine

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 5900-13-0.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5900-13-0, name is 5-Bromo-3-methoxypyrazin-2-amine, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C5H6BrN3O

Intermediate Example lnt-3: ferf-Butyl {1-[4-(6-bromo-8-methoxy-3-phenylimidazo[1,2-a]pyrazin-2 l)phenyl]cyclobutyl}carbamate A mixture of crude fert-butyl (1-{4-[bromo(phenyl)acetyl]phenyl}cyclobutyl)- carbamate [lnt-1-A] (203 mg, 0.38 mmol, 1.0 eq), 5-bromo-3-methoxypyrazin-2- amine (74.6 mg, 0.38 mmol, 1 eq.; Jiang, B. et al. Bioorg. Med. Chem (2001), 9, 1 149-1154.) and diisopropylethylamine (0.064 ml_, 0.38 mmol, 1.0 eq) in 2.3 ml_ butyronitril was heated to 120 for 17 hours and t o 125 *C for 6h. The reaction mixture was concentrated in vacuo. The crude mixture was purified via preparative HPLC under basic conditions (column: Waters X-Bridge, eluent: ACN/water (15/85) -> ACN/water 55/45) to deliver 9 mg (4%) of the title compound. UPLC-MS (Method 2): RT = 1.62 min; m/z = 549 (M) +.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 5900-13-0.