Adding a certain compound to certain chemical reactions, such as: 117719-17-2, name is 5-Bromo-3-morpholinopyrazin-2-amine, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 117719-17-2, Recommanded Product: 117719-17-2
Compound 10 (6.5 g, 25.086 mmol, 1.0 equiv) and ethyl bromopyruvate (3.462 mL, 27.595 mmol, 1.1 equiv) were mixed in the minimum amount of dimethoxyethane (DME). The mixture was refluxed for 20 h. The solvent was evaporated and the residue was purified by automated chromatography (Biotage, EtOAc in cyclohexane, 5-10%) to yield 3.086 g of compound 11 (35% yield).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 5-Bromo-3-morpholinopyrazin-2-amine, and friends who are interested can also refer to it.