Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 36070-80-1, name is 5-Chloropyrazine-2-carboxylic acid, A new synthetic method of this compound is introduced below., Recommanded Product: 36070-80-1
To a 0 C mixture of 5-chloropyrazine-2-carboxylic acid (1.0 g, 6.31 mmol) in DCM (6.3 mi ,) was added oxalyl chloride (6.3 mL, 12.6 mmol) and several drops of DMF. The mixture was stirred at RT overnight, then was concentrated in vacuo to provide the title compound, which was used in the next step without further purification.
The synthetic route of 36070-80-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BRISTOL-MYERS SQUIBB COMPANY; CHENG, Peter Tai Wah; KALTENBACH, Robert F., III.; ZHANG, Hao; SHI, Yan; LI, Jun; (166 pag.)WO2019/126084; (2019); A1;,
Pyrazine – Wikipedia,
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