Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 87486-33-7, name is 3,5-Dichloro-1-methylpyrazin-2(1H)-one, A new synthetic method of this compound is introduced below., Computed Properties of C5H4Cl2N2O
bl .2) Compound (3) A solution of compound (2) (40 g, 223 mmol) and 2-butynedioic acid dimethyl ester (950 g, 670 mmol) in xylene (400 ml) was heated at 145C overnight. The mixture was allowed to cool to r.t.. The reaction mixture was filtered to afford compound (3) (29.5 g, 50.8% yield). LC-MS (ESI+): m/e 260 (M+H)+, Rt: 1.50 min; 1H- NMR(DMSO-Patent; ABBVIE DEUTSCHLAND GMBH & CO. KG; ABBVIE INC.; GENESTE, Herve; OCHSE, Michael; DRESCHER, Karla; BEHL, Berthold; LAPLANCHE, Loic; DINGES, Juergen; JAKOB, Clarissa; WO2014/140184; (2014); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem