Related Products of 951626-95-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 951626-95-2, name is Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.
General procedure: To the stirring solution of compound 6a (45 mg,0.18 mmol) in THF (5 mL) was added sodium hydride (9 mg, 0.21 mmol) in portions at 0C and allowed to stir at room temperature for 15 minutes. Reaction mixture was again re-cooled to 0C and thereto was added 3,4-dichlorobenzyl chloride (56 mg,0.22 mmol drop wise and reaction mixture was allowed to stir at room temperature for 15 h. Reaction mixture was poured in ice-chilled water (50 mL) and extracted with ethyl acetate (2 x 50 mL). The combined organic layer was washed with water (40 mL) followed by brine (10 mL), dried over anhydrous sodium sulphate, filtered and the filtrate was evaporated to dryness. The purification using flash column chromatography on silica gel (100-200 mesh) using MeOH in DCM afforded off white colored solid compound 1(65 mg, 89%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate, other downstream synthetic routes, hurry up and to see.