Adding a certain compound to certain chemical reactions, such as: 54013-04-6, name is Ethyl 5-chloropyrazine-2-carboxylate, belongs to Pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 54013-04-6, category: Pyrazines
Ethyl 5-chloro-2-pyrazinecarboxylate (1.74 mmol) was added hydrazine monohydrate (1 mL) and heated 100 C for1 h. Then ethanol was added (10 mL), the mixture was refluxed for 3 h, finally filtered and washed with ethanol[19]. Brown crystals from ethanol. lambda max. (EtOH) (nm) (logepsilon): 203 (4.69), 279 (5.21), 327 (4.79); IR max.(cm-1): 3327,3277, 3100, 1627, 1568, 1537, 1496, 1197, 1116, 889, 696; 1H-NMR (300 MHz), (DMSO-d6/TMS) ppm: 4.42 (d, 2H,NH2), 8.45 (s, 1H, pyrazine H6 ), 8.61 (s, 1H, pyrazine H3),9.41 (s, 1H, NH). Anal. Cal. for C5H5ClN4O (M.W.: 172.572g/mol): C, 34.80; H, 2.92; N, 32.47. Found: C, 34.60; H,2.90; N, 32.00
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Ethyl 5-chloropyrazine-2-carboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Kocyigit-Kaymakcioglu, Bedia; Yazici, Senem Sinem; Tok, Fatih; Dikmen, Miri?; Enguer, Selin; Oruc-Emre, Emine Elcin; Iyidogan, Aysegul; Letters in drug design and discovery; vol. 16; 5; (2019); p. 522 – 532;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem