Synthetic Route of 6705-33-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 6705-33-5, name is Pyrazin-2-ylmethanol belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below.
Pyrazin-2-ylmethanol (103 mg, 0.094 mmol) and thionyl chloride (546 mg, 4.59 mmol) were dissolved inDichloromethane (15 mL) and reacted for 3 h. The reaction mixture was poured into water (30 mL), extracted with ethyl acetate (30 mL ¡Á 3), and saturated saltWashed with water (15 mL) and dried over anhydrous sodium sulfate. The solvent was removed and the residue was subjected to column chromatography (eluent: PE / EtOAc (v / v)= 10/1) to obtain 87 mg of a pale yellow oil, yield: 72.34%.
The synthetic route of Pyrazin-2-ylmethanol has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Liu Bing; Bai Shun; Zhou Youbo; Yang Tiping; He Wei; Zhang Yingjun; Zheng Changchun; (103 pag.)CN106749268; (2017); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem