Synthetic Route of 109-08-0,Some common heterocyclic compound, 109-08-0, name is 2-Methylpyrazine, molecular formula is C5H6N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
S1:30ml of absolute ethanol,0.2mol / L of 2-methylpyrazine and 1.25mol / L of potassium hydroxide solution into 200mL autoclave,Under 1.5MPa oxygen pressure magnetic stirring 1.5h,Then add 5.0 ¡Á 10-5mol / L of the catalyst was added to the reaction,In the magnetic stirring process,200mL autoclave was heated,And the heating temperature is maintained at 120 ;
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-Methylpyrazine, its application will become more common.
Reference:
Patent; Henan Engineering College; Zhang Qian; He Li; Li Yue; Chen Lei; Zhao Longtao; (6 pag.)CN106831612; (2017); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem