Reference of 89283-32-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 89283-32-9, name is (3-Chloropyrazin-2-yl)methanol, This compound has unique chemical properties. The synthetic route is as follows.
To (3-chloropyrazin-2-yl)methanol of step 1 was dropwise added a solution of SOCI2 (700mg, 5.89mmol) in DMF (10ml) at 0C. Stirring at 0C for 30 min was followed by extraction with ethyl acetate. The organic layer was washed with a saturated NaHC03 solution, dried over anhydrous magnesium sulfate, filtered, and concentrated in a vacuum. The residue was used in a subsequent step without further purification.
The chemical industry reduces the impact on the environment during synthesis (3-Chloropyrazin-2-yl)methanol. I believe this compound will play a more active role in future production and life.
Reference:
Patent; DONG-A ST CO.,LTD; PARK, Jang Hyun; SONG, Seung Hyun; CHUNG, Han Kook; KIM, Heung Jae; LEE, Ji Hye; JANG, Byeong Jun; KIM, Eun Jung; JUNG, Hae Hum; RYU, Chae Lim; HWANG, Jae-Sung; LEE, Hyung Ki; KANG, Kyung Koo; KIM, Soon Hoe; WO2014/157994; (2014); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem