Related Products of 4744-50-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4744-50-7, name is 2,3-Pyrazinecarboxylic anhydride, This compound has unique chemical properties. The synthetic route is as follows.
In a 100 mL flask, 110 2,3-pyrazinedicarboxylic anhydride 12 (0.7505 g, 5 mmol) was reacted with 13 2 (1.0511 g, 5 mmol) in dry 67 THF (10 mL) stirred overnight at rt. The mixture was transferred to a separatory funnel and extracted with CH2Cl2 (3¡Á10 mL) and NaOH (1N) (10 mL). The organic phase was separated and 74 HCl (1N) (10 mL) was added to the aqueous phase until a pH=2 was reached and a 111 precipitate formed. The solid was filtered and washed with water (20 mL), and concentrated under reduced pressure to provide 13 (1.73 g, 4.8 mmol, 96%), as a yellow solid. 1H NMR (400 MHz, DMSO-d6) delta 1.33 (3H, t, J=7.02 Hz), 2.51 (4H, d, J=1.59 Hz), 4.46 (2H, q, J=7.01 Hz), 7.21 (1H, t, J=7.52 Hz), 7.47 (1H, t, J=7.66), 7.59 (1H, d, J=4.10 Hz), 7.61 (1H, d, J=3.48 Hz), 7.73 (1H, d, J=7.27 Hz), 8.58 (1H, s), 8.63 (2H, s); 13C NMR (100 MHz, DMSO-d6) delta 14.2, 37.5, 109.4, 109.7, 110.95, 119.1, 119.7, 120.6, 122.3, 122.6, 126.2, 131.8, 136.8, 140.5, 141.8, 144.8, 145.8, 164.3.
The chemical industry reduces the impact on the environment during synthesis 2,3-Pyrazinecarboxylic anhydride. I believe this compound will play a more active role in future production and life.
Reference:
Patent; UNIVERSITY OF PUERTO RICO; HERNANDEZ-O’FARRILL, Eliud; VLAAR, Cornelis P.; DHARMAWARDHANE FLANAGAN, Suranganie; CASTILLO-PICHARDO, Linette; (52 pag.)US2019/125746; (2019); A1;,
Pyrazine – Wikipedia,
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