Extended knowledge of 3,6-Dichloropyrazin-2-amine

The synthetic route of 14399-37-2 has been constantly updated, and we look forward to future research findings.

Related Products of 14399-37-2, A common heterocyclic compound, 14399-37-2, name is 3,6-Dichloropyrazin-2-amine, molecular formula is C4H3Cl2N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Stage A: preparation of 5,8-dichlorimidazo[1,2-a]pyrazine This derivative is obtained according to a technique identical to that of Example 1, stage A, by replacing 2-aminopyrazine by 2-amino-3,6-dichloropyrazine. 2.4 grams (18.6 mmol) of this compound yield 1 g (Yld=37%) of 5,8-dichloroimidazo[1,2-a]pyrazine (m.p. 102 C.).

The synthetic route of 14399-37-2 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; l’Universite de Montpellier I; US5028605; (1991); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem