Related Products of 75907-74-3, These common heterocyclic compound, 75907-74-3, name is (3,5,6-Trimethylpyrazin-2-yl)methanol, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
(4) In a round bottom flask, add formula (4) (1.0 equiv), using DCM as solvent.Add phosphorus tribromide (1.0-2.0 equiv) at 0 C, stir the reaction at 25 C for 1 h, TLC monitoring formula (4) disappeared, after the reaction was completed, water was added, dichloromethane was extracted, and the organic layer was collected.Drying and concentrating gave the compound of the formula (5) as a white solid.
Statistics shows that (3,5,6-Trimethylpyrazin-2-yl)methanol is playing an increasingly important role. we look forward to future research findings about 75907-74-3.
Reference:
Patent; Chengdu University; Zou Liang; Zhang Jinming; Li Junlong; Liu Xiaowei; Li Wei; Shen Xudong; Dai Liping; Zhuo Hongyi; (13 pag.)CN108440512; (2018); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem