Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 22047-25-2, Name is Acetylpyrazine, molecular formula is C6H6N2O, belongs to Pyrazines compound. In a document, author is Wang, Si-Qing, introduce the new discover, HPLC of Formula: C6H6N2O.
Copper(I)-Catalyzed Asymmetric Vinylogous Aldol-Type Reaction of Allylazaarenes
A vinylogous aldol-type reaction of allylazaarenes and aldehydes is disclosed that affords a series of chiral gamma-hydroxyl-alpha,beta-unsaturated azaarenes in moderate to excellent yields with high to excellent regio- and enantioselectivities. With (R,R-P)-TANIAPHOS and (R,R)-QUINOXP* as the ligand, the carbon-carbon double bond in the products is generated in (E)-form. With (R)-DTBM-SEGPHOS as the ligand, (Z)-form carbon-carbon double bond is formed in the major product. In this vinylogous reaction, aromatic, alpha,beta-unsaturated, and aliphatic aldehydes are competent substrates. Moreover, a variety of azaarenes, such as pyrimidine, pyridine, pyrazine, quinoline, quinoxaline, quinazoline, and benzo[d]imidazole are well-tolerated. At last, the chiral vinylogous product is demonstrated as a suitable Michael acceptor towards CuI-catalyzed nucleophilic addition with organomagnesium reagents.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 22047-25-2. HPLC of Formula: C6H6N2O.