Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Wang, Shengqiang, once mentioned the application of 22047-25-2, Name is Acetylpyrazine, molecular formula is C6H6N2O, molecular weight is 122.1246, MDL number is MFCD00006134, category is Pyrazines. Now introduce a scientific discovery about this category, Category: Pyrazines.
Ag-catalyzed decarboxylative acylation of pyridazines using alpha-keto acids in aqueous media
An efficient and general protocol for Ag-Catalyzed decarboxylative acylation of pyridazines using alpha-keto acids as acylation reagent in aqueous media has been described. This method provides a new avenue for the synthesis of diverse array of acylated pyridazines with different substitution patterns. The reaction proceeds smoothly in water under mild conditions and exhibits a good functional group tolerance. (C) 2020 Elsevier Ltd. All rights reserved.
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