110223-15-9, name is 2-Amino-3-benzyloxypyrazine, belongs to Pyrazines compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Computed Properties of C11H11N3O
General procedure: 2-Amino-3-benzyloxypyridine or pyrazine derivative(2.5 mmol) was dissolved in dry THF (10 mL), isocyanate derivative(3.0 mmol) was added to the reaction mixture. The reaction wasrefluxed for 3-6 h. After cooling, the reaction mixture was evaporated and the residue was purified by solidification with cold methanol and filtered to give the target compounds.
The synthetic route of 110223-15-9 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H.E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Roh, Eun Joo; European Journal of Medicinal Chemistry; vol. 144; (2018); p. 529 – 543;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem