Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 56423-63-3, name is 2-Bromopyrazine, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 56423-63-3
Example 117BPreparation of Compound (142b)(142b)[00659] To a solution of compound (142a) (1.00 g, 2.27 mmol) in dioxane (30 mL) was added K2C03 (1.57 g, 11.4 mmol, 5 equiv.), Pd(PPh3)2Cl2 (30 mg, 3%) and 2-bromopyrazine (720 mg, 4.45 mmol, 2 equiv.). The mixture was degassed within an ultrasonic cleaner for 1 hr. Under argon protection, the reaction mixture was stirred at 90 C for 4 hr. The mixture was cooled to room temperature. The solvents were evaporated under reduced pressure. The residue was purified through FCC to give 460 mg of compound (142b). Characteristic analytical data: 1H NMR 8.67 (1H), 8.46 (1H), 8.32 (1H), 6.47 (1H, vinyl), 5.39 (1H), 4.54-4.62 (m, 1H, AcOCH).
According to the analysis of related databases, 56423-63-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BIOMARIN PHARMACEUTICAL INC.; CHU, Daniel; WANG, Bing; YE, Tao; WO2012/83112; (2012); A2;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem