Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 56423-63-3, name is 2-Bromopyrazine, A new synthetic method of this compound is introduced below., Application In Synthesis of 2-Bromopyrazine
Crystals of 2 were obtained by the slow-diffusion method between 3 layers: 1st layer is a solution of Fe(OTs)2*6H2O(0.096 g, 0.2 mmol, 1 equiv.) and NH4SCN (0.030 g, 0.4 mmol, 1 equiv.) in a water/methanol mixture (1/1, 10 ml); 2nd one is a water/methanol mixture (1/1, 10 ml); 3rd one is a solution of 2-bromopyrazine (0.127 g, 0.8 mmol, 1 equiv.) in methanol (3 ml). After 2 weeks red plates grew in the second layer; they were collected, washed with water and dried in air. Yield is 0.050 g (50%). Anal. Calc. for Fe1C18H16O2N10S2Br4: C, 25.59; H, 1.90; N, 16.58; S,7.58. Found: C, 24.91; H, 1.77; N, 16.42; S, 7.67%. Principal IR absorption bands for 2 (cm-1): 2080 (s), 1510 (m), 1456 (m),1381 (s), 1130 (s), 1057 (m), 1056 (m), 1020 (s).
The synthetic route of 56423-63-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Shylin; Gural Skiy; Bykov; Demeshko; Dechert; Meyer; Hauka; Fritsky; Polyhedron; vol. 87; (2015); p. 147 – 155;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem